Asian Sand Dust Enhances Allergen-Induced Th2 Allergic Inflammatory Changes and Mucin Production in BALB/c Mouse Lungs
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منابع مشابه
Asian Sand Dust Enhances Allergen-Induced Th2 Allergic Inflammatory Changes and Mucin Production in BALB/c Mouse Lungs
PURPOSE Recent studies have reported that Asian sand dust (ASD) has a potential risk of aggravating airway inflammation. The purpose of this study was to investigate the effect of ASD on inflammation and mucin production in the airways of allergic mice. METHODS FORTY BALB/C FEMALE MICE WERE DIVIDED INTO FOUR GROUPS: saline (group 1); ASD (group 2); ovalbumin (OVA) alone (group 3); and OVA+ASD...
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OBJECTIVES Asia sand dust (ASD) is known to cause various human diseases including respiratory infection. The aim of this study was to examine the effect of ASD on inflammatory response in human middle ear epithelial cells (HMEECs) in vitro and in vivo. METHODS Cell viability was assessed using the cell counting kit-8 assay. The mRNA levels of various genes including COX-2, TNF-a, MUC 5AC, MU...
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متن کامل5-BDBD ameliorates an OVA-induced allergic asthma by the reduction of Th2 cytokines production
Objective(s): P2X4R is expressed in immunocyte and lung tissues. It has been a focus in inflammatory responses recently. This study investigated whether blockage of P2X4R attenuates allergic inflammation by modulating T cell response in ovalbumin-sensitized mice. Materials and Methods: Ovalbumin was used to sensitize and challenge for a mouse model. Intranasal application of 5-BDBD, P2X4R antag...
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ژورنال
عنوان ژورنال: Allergy, Asthma & Immunology Research
سال: 2012
ISSN: 2092-7355,2092-7363
DOI: 10.4168/aair.2012.4.4.206